在调试中工作正常，但在发布模式下却出错

Question

请问这是什么意思，如何解决这个错误？ 我的项目在调试模式下工作正常，但在发布模式下却包含错误。 我该如何解决？ 谢谢。

System.OperationCanceledException: Script entries not loaded yet.    
System.Web.HttpUnhandledException (0x80004005): Exception of type 'System.Web.HttpUnhandledException' was thrown. ---> System.OperationCanceledException: Script entries not loaded yet.
   at AjaxControlToolkit.ToolkitScriptManagerCombiner.IsScriptRegistered(ScriptReference scriptReference)
   at AjaxControlToolkit.ToolkitScriptManager.OnResolveScriptReference(ScriptReferenceEventArgs e)
   at System.Web.UI.ScriptManager.RegisterScripts()
   at System.Web.UI.ScriptManager.OnPagePreRenderComplete(Object sender, EventArgs e)
   at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)
   at System.Web.UI.Page.HandleError(Exception e)
   at System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)
   at System.Web.UI.Page.ProcessRequest(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint)
   at System.Web.UI.Page.ProcessRequest()
   at System.Web.UI.Page.ProcessRequest(HttpContext context)
   at System.Web.HttpApplication.CallHandlerExecutionStep.System.Web.HttpApplication.IExecutionStep.Execute()
   at System.Web.HttpApplication.ExecuteStep(IExecutionStep step, Boolean& completedSynchronously)